Friday, October 1, 2010

Autograft Vs Allograft


So what is the difference between autograft and allograft reconstructions? Basically, the autograft is a tendon that is harvested from elsewhere in your own body and used as a replacement ACL. The ones that are typically used are part of the patellar tendon (it joins the kneecap to your shin) or a part of your hamstring. The allograft is a donor tendon from a cadaver, usually the achilles tendon is used.

I've been researching autografts and allografts for days now and there doesn't seem to be a clear favorite. The patellar autograft is often referred to as the "Gold Standard" for ACL repair, but research on other grafts is scant. Here is a summary of what I've found so far:


Allograft (Positives)
- Less pain in recovery as the surgery is just for reconstructing the ACL, there is no donor site.
- Rehab is much shorter as there is no donor site to rehabilitate.
- Surgery is quicker and less expensive.

Allograft (Negatives)
- Risk of disease transmission such as HIV, Hepatitis and more.
- Treatment of tendon for disease and preservation may weaken it.
- Takes longer for the tendon to vascularize (around 9 months).
- Higher failure rate than autografts.
- May not be sufficiently strong to endure frequent sporting 

Patellar Autograft (Positives)
- Considered the "Gold Standard" by which other grafts are measured.
- No doubts about tissue quality or disease transmission.
- Quicker vascularization (around 3-4 months).
- Higher success rate.

Patellar Autograft (Negatives)
- More pain and rehabilitation required.
- Possible numbness at donor site



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